MARCO Antikörper (AA 380-460)

Produktnummer ABIN7229568

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch MARCO in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für MARCO Antikörper (AA 380-460) (ABIN7229568)

Target: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser MARCO Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-MARCO Antikörper

Bindungsspezifität: AA 380-460

Verwendungszweck: Rabbit Anti-MARCO Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of MARCO protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human MARCO protein at AA range: 380-460

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu MARCO

Target: MARCO (Macrophage Receptor with Collagenous Structure (MARCO))

Andere Bezeichnung: MARCO

Hintergrund: Macrophage receptor MARCO, Macrophage receptor with collagenous structure, Scavenger receptor class A member 2The protein encoded by MARCO (Macrophage Receptor With Collagenous Structure) is a member of the class A scavenger receptor family and is part of the innate antimicrobial immune system. The protein may bind both Gram-negative and Gram-positive bacteria via an extracellular, C-terminal, scavenger receptor cysteine-rich (SRCR) domain. In addition to short cytoplasmic and transmembrane domains, there is an extracellular spacer domain and a long, extracellular collagenous domain. The protein may form a trimeric molecule by the association of the collagenous domains of three identical polypeptide chains.

Molekulargewicht: 57kD

Gen-ID: 8685

UniProt: Q9UEW3

Pathways: Activation of Innate immune Response