KDM3B Antikörper (AA 230-310)

Produktnummer ABIN7229268

Der Kaninchen Polyklonal anti-KDM3B Antikörper wird verwendet zum Nachweis von KDM3B in Proben von Human und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für KDM3B Antikörper (AA 230-310) (ABIN7229268)

Target: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser KDM3B Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-KDM3B Antikörper

Bindungsspezifität: AA 230-310

Verwendungszweck: Rabbit Anti-KDM3B Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of KDM3B protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human KDM3B protein at AA range: 230-310

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu KDM3B

Target: KDM3B (Lysine (K)-Specific Demethylase 3B (KDM3B))

Andere Bezeichnung: KDM3B

Hintergrund: Lysine-specific demethylase 3B, JmjC domain-containing histone demethylation protein 2B, Jumonji domain-containing protein 1B, Nuclear protein 5qNCAKDM3B (Lysine Demethylase 3B) is a Protein Coding gene. Diseases associated with KDM3B include Persistent Hyperplastic Primary Vitreous. Among its related pathways are Chromatin organization and Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3. Histone demethylase that specifically demethylates Lys-9 of histone H3, thereby playing a central role in histone code. Demethylation of Lys residue generates formaldehyde and succinate. May have tumor suppressor activity.

Molekulargewicht: 193kD

Gen-ID: 51780

UniProt: Q7LBC6

Pathways: Warburg Effekt