LRP3 Antikörper (AA 30-110)

Produktnummer ABIN7222266

Dieser Anti-LRP3 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von LRP3 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für LRP3 Antikörper (AA 30-110) (ABIN7222266)

Target: LRP3 (Low Density Lipoprotein Receptor-Related Protein 3 (LRP3))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser LRP3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-LRP3 Antikörper

Bindungsspezifität: AA 30-110

Verwendungszweck: LRP3 Polyclonal Antibody

Spezifität: LRP3 Polyclonal Antibody detects endogenous levels of LRP3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human LRP3 at AA range: 30-110

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu LRP3

Target: LRP3 (Low Density Lipoprotein Receptor-Related Protein 3 (LRP3))

Andere Bezeichnung: LRP3

Hintergrund: Rabbit Anti-LRP3 Polyclonal Antibody,LRP3, Low-density lipoprotein receptor-related protein 3, LRP-3, 105 kDa low-density lipoprotein receptor-related protein, hLRp105,NLRP3, also known as NALP3, CIAS1, PYPAF or Cryopyrin, is a cytosolic ~120 kDa member of the NLRP family of proteins expressed in leukocytes, especially neutrophils. As a component of the inflammasome, NLRP3 activates caspases 1 and 5. Defects in NLRP3 may cause FCAS1, CINCA, or Muckle-Wells autoinflammatory syndromes. Mouse NLRP3 contains an N-terminal Pyrin domain (aa 1-91) followed by a Nacht region (aa 216-532), and seven LRRs (aa 739-988). Within the sequence used as an immunogen, mouse NLRP3 shares 78 % and 93 % aa identity with human and rat NLRP3, respectively. Alternate splicing of mouse NLRP3 generates additional isoforms that lack either LRR2 and 3, LRR 6 and 7, or LRR4-9.,Low-density lipoprotein receptor-related protein 3

Molekulargewicht: observerd band 80kDa

Gen-ID: 4037

UniProt: O75074