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LRP3 Antikörper (C-Term)

LRP3 Reaktivität: Human WB, IHC (p) Wirt: Kaninchen Polyclonal RB2239 unconjugated
Produktnummer ABIN390097
  • Target Alle LRP3 Antikörper anzeigen
    LRP3 (Low Density Lipoprotein Receptor-Related Protein 3 (LRP3))
    Bindungsspezifität
    • 4
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 661-692, C-Term
    Reaktivität
    • 18
    • 12
    • 12
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 16
    • 2
    Kaninchen
    Klonalität
    • 16
    • 2
    Polyklonal
    Konjugat
    • 11
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser LRP3 Antikörper ist unkonjugiert
    Applikation
    • 10
    • 8
    • 3
    • 3
    • 1
    • 1
    • 1
    Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
    Aufreinigung
    This antibody is purified through a protein A column, followed by peptide affinity purification.
    Immunogen
    This LRP3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 661-692 amino acids from the C-terminal region of human LRP3.
    Klon
    RB2239
    Isotyp
    Ig Fraction
    Top Product
    Discover our top product LRP3 Primärantikörper
  • Applikationshinweise
    WB: 1:2000. IHC-P: 1:10~50
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    4 °C,-20 °C
    Informationen zur Lagerung
    Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
    Haltbarkeit
    6 months
  • Target
    LRP3 (Low Density Lipoprotein Receptor-Related Protein 3 (LRP3))
    Andere Bezeichnung
    LRP3 (LRP3 Produkte)
    Synonyme
    LRP3 antikoerper, LDL receptor related protein 3 antikoerper, LDL receptor related protein 3 S homeolog antikoerper, low density lipoprotein receptor-related protein 3 antikoerper, LRP3 antikoerper, lrp3.S antikoerper, Lrp3 antikoerper
    Hintergrund
    Low density lipoprotein (LDL) receptor-related protein (LRP), a member of the LDL receptor family, binds multiple classes of ligands and has been implicated in a broad range of normal and disease processes involving lipid metabolism, protease clearance, and cell migration (1). Structurally, members of the LDLR family share homology within their extracellular domains, which are highlighted by the presence of clusters of ligand-binding repeats. LRP is a large endocytic receptor that participates in several biological pathways and plays prominent roles in lipoprotein metabolism and in the catabolism of proteinases involved in coagulation and fibrinolysis. LRP also mediates the cellular entry of certain viruses and toxins and facilitates the activation of various lysosomal enzymes (2). All LRPs are expressed in the central nervous system and, for most receptors, animal models have shown that they are indispensable for successful neurodevelopment. The mechanisms by which they regulate the formation of the nervous system are varied and include the transduction of extracellular signals and the modulation of intracellular signal propagation, as well as cargo transport, the function most commonly attributed to this gene family (3).
    Molekulargewicht
    82884
    Gen-ID
    4037
    NCBI Accession
    NP_002324
    UniProt
    O75074
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