Kallikrein 8 Antikörper (Cleaved-Val33)
Kurzübersicht für Kallikrein 8 Antikörper (Cleaved-Val33) (ABIN7212480)
Target
Alle Kallikrein 8 (KLK8) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 30-110, Cleaved-Val33
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Verwendungszweck
- Cleaved-KLK8 (V33) Polyclonal Antibody
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Spezifität
- Cleaved-KLK8 (V33) Polyclonal Antibody detects endogenous levels of fragment of activated KLK8 protein resulting from cleavage adjacent to V33.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the N-terminal region of human KLK8 at AA range: 30-110
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Kallikrein 8 (KLK8)
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Andere Bezeichnung
- KLK8
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Hintergrund
- Rabbit Anti-Cleaved-KLK8 (V33) Polyclonal Antibody,KLK8, NRPN, PRSS19, TADG14, Kallikrein-8, hK8, Neuropsin, NP, Ovasin, Serine protease 19, Serine protease TADG-14, Tumor-associated differentially expressed gene 14 protein,Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. KLK8 is one of the fifteen kallikrein subfamily members located in tandem in a gene cluster on chromosome 19. Kallikrein related peptidase 8 may be involved in proteolytic cascade in the skin and may serve as a biomarker for ovarian cancer. Alternate splicing of KLK8 results in multiple transcript variants encoding different isoforms.,Kallikrein-8
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Molekulargewicht
- observerd band 24kDa
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Gen-ID
- 11202
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UniProt
- O60259
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Pathways
- Komplementsystem
Target
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