JunB Antikörper

Produktnummer ABIN7221960

Der Kaninchen Polyklonal anti-JunB Antikörper wird verwendet zum Nachweis von JunB in Proben von Human und Maus. Er wurde validiert für WB, IHC, IP, ELISA und IF.

Kurzübersicht für JunB Antikörper (ABIN7221960)

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser JunB Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Immunoprecipitation (IP), ELISA, Immunofluorescence (IF)

Produktdetails anti-JunB Antikörper

Verwendungszweck: Rabbit Anti-Jun B Polyclonal Antibody

Spezifität: Jun B Polyclonal Antibody detects endogenous levels of Jun B protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human Jun B around the non-phosphorylation site of S259

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IP 2-5 μg:mg lysate,ELISA 1:20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu JunB

Target: JunB (JUNB) (Jun B Proto-Oncogene (JUNB))

Andere Bezeichnung: Jun B

Hintergrund: JUNB, Transcription factor jun-BJunB is a basic region, leucine zipper (bZIP) transcription factor belonging to the Jun family that includes c-Jun and JunD. Jun family members homodimerize or heterodimerize with Fos and ATF proteins to form a functional transcription factor AP-1 (activator protein 1), whose activity is regulated by a variety of physiological and pathological stimuli such as growth factors, infections, and stress signals. While JunB sometimes antagonizes c-Jun transcriptional activity, it may functionally substitute for c-Jun during development in mice. JunB regulates hematopoietic stem cell number and plays an important role in the pathogenesis of chronic myelogenous leukemia (CML) and acute myeloid leukemia (AML).

Molekulargewicht: 36kD

Gen-ID: 3726

UniProt: P17275