Inversin Antikörper

Produktnummer ABIN7229172

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Inversin in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human und Maus.

Kurzübersicht für Inversin Antikörper (ABIN7229172)

Target: Inversin (INVS)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Inversin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Inversin Antikörper

Verwendungszweck: INVS Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of INVS protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human INVS protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Inversin

Target: Inversin (INVS)

Andere Bezeichnung: INVS

Hintergrund: Rabbit Anti-INVS Polyclonal Antibody,Inversin, Inversion of embryo turning homolog, Nephrocystin-2,INVS (Inversin) is a Protein Coding gene. Diseases associated with INVS include Nephronophthisis 2, Infantile and Nephronophthisis 16. Among its related pathways are Wnt Signaling Pathway and Pluripotency. INVS encodes a protein containing multiple ankyrin domains and two IQ calmodulin-binding domains. The encoded protein may function in renal tubular development and function, and in left-right axis determination. This protein interacts with nephrocystin and infers a connection between primary cilia function and left-right axis determination. A similar protein in mice interacts with calmodulin. Mutations in INVS have been associated with nephronophthisis type 2. Multiple transcript variants encoding distinct isoforms have been identified for INVS.,INVS

Molekulargewicht: observerd band 117kDa

Gen-ID: 27130

UniProt: Q9Y283