IL2 Receptor beta Antikörper (pTyr364)

Produktnummer ABIN7221758

Der Kaninchen Polyklonal anti-IL2 Receptor beta Antikörper (ABIN7221758) detektiert spezifisch IL2 Receptor beta in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Maus, Human, Ratte und Affe.

Kurzübersicht für IL2 Receptor beta Antikörper (pTyr364) (ABIN7221758)

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Reaktivität: Maus, Human, Ratte, Affe

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IL2 Receptor beta Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-IL2 Receptor beta Antikörper

Bindungsspezifität: pTyr364

Verwendungszweck: IL-2Rβ (phospho Tyr364) Polyclonal Antibody

Spezifität: Phospho-IL-2Rβ (Y364) Polyclonal Antibody detects endogenous levels of IL-2Rβ protein only when phosphorylated at Y364.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human IL-2Rbeta Phospho-Tyr364

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu IL2 Receptor beta

Target: IL2 Receptor beta (IL2RB) (Interleukin 2 Receptor, beta (IL2RB))

Andere Bezeichnung: IL-2Rbeta

Hintergrund: Rabbit Anti-IL-2Rβ (phospho Tyr364) Polyclonal Antibody,IL2RB, Interleukin-2 receptor subunit beta, IL-2 receptor subunit beta, IL-2R subunit beta, IL-2RB, High affinity IL-2 receptor subunit beta, p70-75, p75, CD antigen CD122,The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. Both the intermediate and high affinity forms of the receptor are involved in receptor-mediated endocytosis and transduction of mitogenic signals from interleukin 2. The protein encoded by IL2RB represents the beta subunit and is a type I membrane protein.,Interleukin-2 receptor subunit beta

Molekulargewicht: observerd band 75kDa

Gen-ID: 3560

UniProt: P14784

Pathways: JAK-STAT Signalweg, Growth Factor Binding