IFNAR1 Antikörper (pTyr466)

Produktnummer ABIN7221686

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch IFNAR1 in WB, ELISA, IHC und IF. Es zeigt Reaktivität gegenüber Proben von Human, Maus und Ratte.

Kurzübersicht für IFNAR1 Antikörper (pTyr466) (ABIN7221686)

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser IFNAR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-IFNAR1 Antikörper

Bindungsspezifität: pTyr466

Verwendungszweck: Rabbit Anti-IFN-α/βRα (phospho Tyr466) Polyclonal Antibody

Spezifität: Phospho-IFN-α/βRα (Y466) Polyclonal Antibody detects endogenous levels of IFN-α/βRα protein only when phosphorylated at Y466.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human IFN-alpha/betaRalpha Phospho-Tyr466

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu IFNAR1

Target: IFNAR1 (Interferon alpha/beta Receptor 1 (IFNAR1))

Andere Bezeichnung: IFN-alpha/betaRalpha

Hintergrund: IFNAR1, IFNAR, Interferon alpha/beta receptor 1, IFN-R-1, IFN-alpha/beta receptor 1, Cytokine receptor class-II member 1, Cytokine receptor family 2 member 1, CRF2-1, Type I interferon receptor 1Interferon alpha and beta receptor subunit 1 encoded by IFNAR1 is a type I membrane protein that forms one of the two chains of a receptor for interferons alpha and beta. Binding and activation of the receptor stimulates Janus protein kinases, which in turn phosphorylate several proteins, including STAT1 and STAT2. The encoded protein also functions as an antiviral factor.

Molekulargewicht: 63kD

Gen-ID: 3454

UniProt: P17181

Pathways: JAK-STAT Signalweg, Hepatitis C