INSRR Antikörper (AA 80-160)

Produktnummer ABIN7229156

Der Kaninchen Polyklonal anti-INSRR Antikörper (ABIN7229156) detektiert spezifisch INSRR in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für INSRR Antikörper (AA 80-160) (ABIN7229156)

Target: INSRR (Insulin Receptor-Related Receptor (INSRR))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser INSRR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-INSRR Antikörper

Bindungsspezifität: AA 80-160

Verwendungszweck: Rabbit Anti-INSRR Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of INSRR protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human INSRR protein at AA range: 80-160

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu INSRR

Target: INSRR (Insulin Receptor-Related Receptor (INSRR))

Andere Bezeichnung: INSRR

Hintergrund: IR-related receptorINSRR (Insulin Receptor Related Receptor) is a Protein Coding gene. Diseases associated with INSRR include Regular Astigmatism and Podoconiosis. Among its related pathways are Akt Signaling and Nanog in Mammalian ESC Pluripotency. GO annotations related to this gene include transferase activity, transferring phosphorus-containing groups and protein tyrosine kinase activity. An important paralog of this gene is IGF1R. Receptor with tyrosine-protein kinase activity. Functions as a pH sensing receptor which is activated by increased extracellular pH . Activates an intracellular signaling pathway that involves IRS1 and AKT1/PKB.

Molekulargewicht: 142kD

Gen-ID: 3645

UniProt: P14616

Pathways: RTK Signalweg