ICOS Antikörper (Internal Region)

Produktnummer ABIN7226680

Der Kaninchen Polyklonal anti-ICOS Antikörper wird verwendet zum Nachweis von ICOS in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für ICOS Antikörper (Internal Region) (ABIN7226680)

Target: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ICOS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-ICOS Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: Rabbit Anti-ICOS Polyclonal Antibody

Spezifität: ICOS Polyclonal Antibody detects endogenous levels of ICOS protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ICOS

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-1:300,ELISA 1:10000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ICOS

Target: ICOS (Inducible T-Cell Co-Stimulator (ICOS))

Andere Bezeichnung: ICOS

Hintergrund: ICOS, AILIM, Inducible T-cell costimulator, Activation-inducible lymphocyte immunomediatory molecule, CD278The protein encoded by ICOS (inducible T-cell costimulator) belongs to the CD28 and CTLA-4 cell-surface receptor family. It forms homodimers and plays an important role in cell-cell signaling, immune responses, and regulation of cell proliferation.

Molekulargewicht: 22kD

Gen-ID: 29851

UniProt: Q9Y6W8

Pathways: Cancer Immune Checkpoints