HCN4 Antikörper (AA 600-680)

Produktnummer ABIN7228872

Der Kaninchen Polyklonal anti-HCN4 Antikörper wird verwendet zum Nachweis von HCN4 in Proben von Human, Ratte und Maus. Er wurde validiert für WB und ELISA.

Kurzübersicht für HCN4 Antikörper (AA 600-680) (ABIN7228872)

Target: HCN4 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 4 (HCN4))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HCN4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HCN4 Antikörper

Bindungsspezifität: AA 600-680

Verwendungszweck: Rabbit Anti-HCN4 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of HCN4 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human HCN4 protein at AA range: 600-680

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu HCN4

Target: HCN4 (Hyperpolarization Activated Cyclic Nucleotide-Gated Potassium Channel 4 (HCN4))

Andere Bezeichnung: HCN4

Hintergrund: Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4HCN4 (Hyperpolarization Activated Cyclic Nucleotide Gated Potassium Channel 4) encodes a member of the hyperpolarization-activated cyclic nucleotide-gated potassium channels. The encoded protein shows slow kinetics of activation and inactivation, and is necessary for the cardiac pacemaking process. This channel may also mediate responses to sour stimuli. Mutations in HCN4 have been linked to sick sinus syndrome 2, also known as atrial fibrillation with bradyarrhythmia or familial sinus bradycardia. Two pseudogenes have been identified on chromosome 15.

Molekulargewicht: 132kD

Gen-ID: 10021

UniProt: Q9Y3Q4