HDAC8 Antikörper (pSer39)

Produktnummer ABIN7212982

Der Kaninchen Polyklonal anti-HDAC8 Antikörper (ABIN7212982) detektiert spezifisch HDAC8 in WB, IHC, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für HDAC8 Antikörper (pSer39) (ABIN7212982)

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HDAC8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-HDAC8 Antikörper

Bindungsspezifität: pSer39

Verwendungszweck: Rabbit Anti-HDAC8 (phospho Ser39) Polyclonal Antibody

Spezifität: Phospho-HDAC8 (S39) Polyclonal Antibody detects endogenous levels of HDAC8 protein only when phosphorylated at S39.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human HDAC8 Phospho-Ser39

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu HDAC8

Target: HDAC8 (Histone Deacetylase 8 (HDAC8))

Andere Bezeichnung: HDAC8

Hintergrund: HDAC8, HDACL1, CDA07, Histone deacetylase 8, HD8Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. Histone deacetylase 8 encoded by HDAC8 belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for HDAC8.

Gen-ID: 55869

UniProt: Q9BY41

Pathways: Cellular Glucan Metabolic Process