HSPB8 Antikörper

Produktnummer ABIN7212116

Dieser Maus Monoklonal Antikörper erkennt spezifisch HSPB8 in WB. Er zeigt eine Reaktivität gegenüber Human, Maus und Ratte.

Kurzübersicht für HSPB8 Antikörper (ABIN7212116)

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Reaktivität: Human, Maus, Ratte

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser HSPB8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-HSPB8 Antikörper

Verwendungszweck: HSPB8/HSP22 Monoclonal Antibody

Aufreinigung: The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen

Immunogen: Recombinant Protein

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:1000-1:2000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu HSPB8

Target: HSPB8 (Heat Shock 22kDa Protein 8 (HSPB8))

Andere Bezeichnung: HSPB8/HSP22

Hintergrund: Mouse Anti-HSPB8/HSP22 Monoclonal Antibody,HSPB8, CRYAC, E2IG1, HSP22, PP1629, Heat shock protein beta-8, HspB8, Alpha-crystallin C chain, E2-induced gene 1 protein, Protein kinase H11, Small stress protein-like protein HSP22,The protein encoded by HSPB8 (heat shock protein family B (small) member 8) belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule. The expression of HSPB8 in induced by estrogen in estrogen receptor-positive breast cancer cells, and this protein also functions as a chaperone in association with Bag3, a stimulator of macroautophagy. Thus, HSPB8 appears to be involved in regulation of cell proliferation, apoptosis, and carcinogenesis, and mutations in HSPB8 have been associated with different neuromuscular diseases, including Charcot-Marie-Tooth disease.,HSPB8

Molekulargewicht: observerd band 22kDa

Gen-ID: 26353

UniProt: Q9UJY1