HAND2 Antikörper

Produktnummer ABIN7228838

Der Kaninchen Polyklonal anti-HAND2 Antikörper wird verwendet zum Nachweis von HAND2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für HAND2 Antikörper (ABIN7228838)

Target: HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HAND2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-HAND2 Antikörper

Verwendungszweck: Rabbit Anti-HAND2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of HAND2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human HAND2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu HAND2

Target: HAND2 (Heart and Neural Crest Derivatives Expressed 2 (HAND2))

Andere Bezeichnung: HAND2

Hintergrund: Heart- and neural crest derivatives-expressed protein 2, Class A basic helix-loop-helix protein 26, bHLHa26, Deciduum, heart, autonomic nervous system and neural crest derivatives-expressed protein 2, dHANDHeart And Neural Crest Derivatives Expressed 2 encoded by HAND2 belongs to the basic helix-loop-helix family of transcription factors. HAND2 product is one of two closely related family members, the HAND proteins, which are asymmetrically expressed in the developing ventricular chambers and play an essential role in cardiac morphogenesis. Working in a complementary fashion, they function in the formation of the right ventricle and aortic arch arteries, implicating them as mediators of congenital heart disease. In addition, this transcription factor plays an important role in limb and branchial arch development. HAND2 (Heart And Neural Crest Derivatives Expressed 2) is a Protein Coding gene. Diseases associated with HAND2 include Saethre-Chotzen Syndrome and Split Hand-Foot Malformation. Among its related pathways are NFAT and Cardiac Hypertrophy and Heart Development.

Molekulargewicht: 23kD

Gen-ID: 9464

UniProt: P61296

Pathways: Tube Formation, Feeding Behaviour