Glycogen Synthase 1 Antikörper (pSer645)

Produktnummer ABIN7221420

Der Kaninchen Polyklonal Anti-Glycogen Synthase 1 Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, Glycogen Synthase 1 in Proben von Human, Maus und Ratte zu detektieren.

Kurzübersicht für Glycogen Synthase 1 Antikörper (pSer645) (ABIN7221420)

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Glycogen Synthase 1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Glycogen Synthase 1 Antikörper

Bindungsspezifität: pSer645

Verwendungszweck: Glycogen Synthase 1 (phospho Ser645) Polyclonal Antibody

Spezifität: Phospho-Glycogen Synthase 1 (S645) Polyclonal Antibody detects endogenous levels of Glycogen Synthase 1 protein only when phosphorylated at S645.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from human Glycogen Synthase 1 Phospho-Ser645

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Glycogen Synthase 1

Target: Glycogen Synthase 1 (GYS1) (Glycogen Synthase 1 (Muscle) (GYS1))

Andere Bezeichnung: Glycogen Synthase 1

Hintergrund: Rabbit Anti-Glycogen Synthase 1 (phospho Ser645) Polyclonal Antibody,GYS1, GYS, Glycogen [starch] synthase, muscle,The glycogen synthase 1 encoded by GYS1 catalyzes the addition of glucose monomers to the growing glycogen molecule through the formation of alpha-1,4-glycoside linkages. Mutations in GYS1 are associated with muscle glycogen storage disease. Alternatively spliced transcript variants encoding different isoforms have been found for GYS1.,Glycogen [starch] synthase muscle

Molekulargewicht: observerd band 83kDa

Gen-ID: 2997

UniProt: P13807

Pathways: PI3K-Akt Signalweg, AMPK Signaling, Cellular Glucan Metabolic Process