Metabotropic Glutamate Receptor 5 Antikörper (AA 40-120)

Produktnummer ABIN7215754

Dieser Anti-Metabotropic Glutamate Receptor 5 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Metabotropic Glutamate Receptor 5 in WB, IF, ELISA und IHC (p). Geeignet für Ratte, Human und Maus.

Kurzübersicht für Metabotropic Glutamate Receptor 5 Antikörper (AA 40-120) (ABIN7215754)

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Reaktivität: Ratte, Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Metabotropic Glutamate Receptor 5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunofluorescence (IF), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Metabotropic Glutamate Receptor 5 Antikörper

Bindungsspezifität: AA 40-120

Verwendungszweck: mGluR5 Polyclonal Antibody

Spezifität: MGluR5 Polyclonal Antibody detects endogenous levels of mGluR5 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the N-terminal region of human mGluR5 at AA range: 40-120

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Metabotropic Glutamate Receptor 5

Target: Metabotropic Glutamate Receptor 5 (GRM5) (Glutamate Receptor, Metabotropic 5 (GRM5))

Andere Bezeichnung: mGluR5

Hintergrund: Rabbit Anti-mGluR5 Polyclonal Antibody,GRM5, GPRC1E, MGLUR5, Metabotropic glutamate receptor 5, mGluR5,GRM5 encodes a member of the G-protein coupled receptor 3 protein family. Metabotropic glutamate receptor 5 is a metabatropic glutamate receptor, whose signaling activates a phosphatidylinositol-calcium second messenger system. Metabotropic glutamate receptor 5 may be involved in the regulation of neural network activity and synaptic plasticity. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. A pseudogene of this gene has been defined on chromosome 11. Alternative splicing results in multiple transcript variants.,Metabotropic glutamate receptor 5

Molekulargewicht: observerd band 130kDa

Gen-ID: 2915

UniProt: P41594

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling, Regulation of long-term Neuronal Synaptic Plasticity