GNS Antikörper (AA 190-270)

Produktnummer ABIN7228700

Der Kaninchen Polyklonal anti-GNS Antikörper (ABIN7228700) detektiert spezifisch GNS in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für GNS Antikörper (AA 190-270) (ABIN7228700)

Target: GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GNS Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GNS Antikörper

Bindungsspezifität: AA 190-270

Verwendungszweck: Rabbit Anti-GNS Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of GNS protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GNS protein at AA range: 190-270

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GNS

Target: GNS (Glucosamine (N-Acetyl)-6-Sulfatase (GNS))

Andere Bezeichnung: GNS

Hintergrund: Glucosamine-6-sulfatase, G6SThe product of GNS is a lysosomal enzyme found in all cells. It is involved in the catabolism of heparin, heparan sulphate, and keratan sulphate. Deficiency of this enzyme results in the accumulation of undegraded substrate and the lysosomal storage disorder mucopolysaccharidosis type IIID (Sanfilippo D syndrome). Mucopolysaccharidosis type IIID is the least common of the four subtypes of Sanfilippo syndrome.

Molekulargewicht: 60kD

Gen-ID: 2799

UniProt: P15586

Pathways: Glycosaminoglycan Metabolic Process