GABARAP Antikörper

Produktnummer ABIN7226848

Der Kaninchen Polyklonal anti-GABARAP Antikörper wird verwendet zum Nachweis von GABARAP in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für GABARAP Antikörper (ABIN7226848)

Target: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GABARAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GABARAP Antikörper

Verwendungszweck: Rabbit Anti-GABARAP Polyclonal Antibody

Spezifität: GABARAP Polyclonal Antibody detects endogenous levels of GABARAP.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthetic Peptide of GABARAP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GABARAP

Target: GABARAP (GABA(A) Receptor-Associated Protein (GABARAP))

Andere Bezeichnung: GABARAP

Hintergrund: GABA(A) receptor-associated protein-like 2GABARAPL2 (also known as Golgi-associated ATPase enhancer of 16 kDa, GATE-16) was originally characterized as a factor essential for intra-Golgi protein transport. Later GABARAPL2 along with LC3 and GABARAP, were identified as the homologs of yeast ATG8 which is a unique ubiquitin-like protein essential for autophagy. When induced GABARAPL2 is first digested by ATG4 family enzymes to become its mature form: gABARAPL2-I, later conjugated to PE lipid as lipidated form: gABARAPL2-II. The lipidated form migrates faster than its mature form on SDS-PAGE gel. GABARAPL2 is strongly expressed in the brain. This antibody is specific to GABARAPL2. It has no cross-reaction to other GABARAP protein.

Molekulargewicht: 17kD

Gen-ID: 11345

UniProt: P60520

Pathways: Autophagie