GPSM2 Antikörper

Produktnummer ABIN7228762

Der Kaninchen Polyklonal anti-GPSM2 Antikörper (ABIN7228762) detektiert spezifisch GPSM2 in WB und ELISA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für GPSM2 Antikörper (ABIN7228762)

Target: GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPSM2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GPSM2 Antikörper

Verwendungszweck: Rabbit Anti-GPSM2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of GPSM2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human GPSM2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GPSM2

Target: GPSM2 (G-Protein Signaling Modulator 2 (GPSM2))

Andere Bezeichnung: GPSM2

Hintergrund: G-protein-signaling modulator 2, Mosaic protein LGNThe protein encoded by GPSM2 belongs to a family of proteins that modulate activation of G proteins, which transduce extracellular signals received by cell surface receptors into integrated cellular responses. The N-terminal half of this protein contains 10 copies of leu-gly-asn (LGN) repeat, and the C-terminal half contains 4 GoLoco motifs, which are involved in guanine nucleotide exchange. This protein may play a role in neuroblast division and in the development of normal hearing. Mutations in this gene are associated with autosomal recessive nonsyndromic deafness (DFNB82). Alternative splicing results in multiple transcript variants. GPSM2 (G Protein Signaling Modulator 2) is a Protein Coding gene. Diseases associated with GPSM2 include Chudley-Mccullough Syndrome and Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb.

Molekulargewicht: 75kD

Gen-ID: 29899

UniProt: P81274

Pathways: Regulation of G-Protein Coupled Receptor Protein Signaling