GRK6 Antikörper (AA 10-90)

Produktnummer ABIN7221274

Der Kaninchen Polyklonal anti-GRK6 Antikörper (ABIN7221274) detektiert spezifisch GRK6 in WB, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für GRK6 Antikörper (AA 10-90) (ABIN7221274)

Target: GRK6 (G Protein-Coupled Receptor Kinase 6 (GRK6))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GRK6 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-GRK6 Antikörper

Bindungsspezifität: AA 10-90

Verwendungszweck: Rabbit Anti-GRK 6 Polyclonal Antibody

Spezifität: GRK 6 Polyclonal Antibody detects endogenous levels of GRK 6 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human GRK 6 at AA range: 10-90

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:10000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu GRK6

Target: GRK6 (G Protein-Coupled Receptor Kinase 6 (GRK6))

Andere Bezeichnung: GRK 6

Hintergrund: GRK6, GPRK6, G protein-coupled receptor kinase 6, G protein-coupled receptor kinase GRK6GRK6 encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The G protein-coupled receptor kinase 6 phosphorylates the activated forms of G protein-coupled receptors thus initiating their deactivation. Several transcript variants encoding different isoforms have been described for GRK6.

Molekulargewicht: 65kD

Gen-ID: 2870

UniProt: P43250

Pathways: Myometrial Relaxation and Contraction, Regulation of G-Protein Coupled Receptor Protein Signaling, CXCR4-mediated Signaling Events, Negative Regulation of Transporter Activity