GPR31 Antikörper (AA 150-230)

Produktnummer ABIN7221238

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch GPR31 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für GPR31 Antikörper (AA 150-230) (ABIN7221238)

Target: GPR31 (G Protein-Coupled Receptor 31 (GPR31))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR31 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-GPR31 Antikörper

Bindungsspezifität: AA 150-230

Verwendungszweck: GPR31 Polyclonal Antibody

Spezifität: GPR31 Polyclonal Antibody detects endogenous levels of GPR31 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human GPR31 at AA range: 150-230

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu GPR31

Target: GPR31 (G Protein-Coupled Receptor 31 (GPR31))

Andere Bezeichnung: GPR31

Hintergrund: Rabbit Anti-GPR31 Polyclonal Antibody,GPR31, 12-(S)-hydroxy-5, 8,10,14-eicosatetraenoic acid receptor, 12-(S)-HETE receptor, 12-HETER, G-protein coupled receptor 31,GPR31 (G Protein-Coupled Receptor 31) is a Protein Coding gene. Among its related pathways are Signaling by GPCR and Peptide ligand-binding receptors. GO annotations related to this gene include G-protein coupled receptor activity. An important paralog of this gene is HCAR3. igh-affinity receptor for 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B.,12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid receptor

Molekulargewicht: observerd band 33kDa

Gen-ID: 2853

UniProt: O00270