GPR31 Antikörper (C-Term)

Produktnummer ABIN5516748

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch GPR31 in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für GPR31 Antikörper (C-Term) (ABIN5516748)

Target: GPR31 (G Protein-Coupled Receptor 31 (GPR31))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser GPR31 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-GPR31 Antikörper

Bindungsspezifität: C-Term

Verwendungszweck: GPR31 Antibody - C-terminal region

Sequenz: QKRLREPEKQ PKLQRAQALV TLVVVLFALC FLPCFLARVL MHIFQNLGSC

Produktmerkmale: This is a rabbit polyclonal antibody against GPR31. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the C-terminal region of Human GPR31

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Kommentare:

We also sell a specific blocking peptide that can be used in combination with this antibody. You can find the blocking peptide under AAP66579-100UG

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5 mg/mL

Buffer: Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: prevent freeze-thaw cycles

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: For short term use, store at 2-8C up to 1 week. For long term storage, store at -20 °C in small aliquots to prevent freeze-thaw cycles.

Details zu GPR31

Target: GPR31 (G Protein-Coupled Receptor 31 (GPR31))

Andere Bezeichnung: GPR31

Hintergrund:

Background Information: GPR31 is a high-affinity receptor for 12-(S)-hydroxy-5,8,10,14- eicosatetraenoic acid (12-S-HETE). 12-(S)-HETE is an arachidonic acid metabolite secreted by platelets and tumor cells, and known to induce endothelial cells retraction allowing invasive cell access to the subendothelial matrix, which is a critical step for extravasation or metastasis. Ligand-binding lead to activation of ERK1/2 (MAPK3/MAPK1), MEK, and NF-kappa-B.

Alternative Symbols: HETER, HETER1, 12-HETER

Molekulargewicht: 35kDa

Gen-ID: 2853

NCBI Accession: NP_005290

UniProt: O00270