Frizzled5/8 Antikörper (AA 10-90)

Produktnummer ABIN7225248

Der Kaninchen Polyklonal anti-Frizzled5/8 Antikörper (ABIN7225248) detektiert spezifisch Frizzled5/8 in WB, ELISA und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für Frizzled5/8 Antikörper (AA 10-90) (ABIN7225248)

Target: Frizzled5/8 (HYFZD5/8)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Frizzled5/8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-Frizzled5/8 Antikörper

Bindungsspezifität: AA 10-90

Verwendungszweck: Rabbit Anti-Frizzled-5/8 Polyclonal Antibody

Spezifität: Frizzled-5/8 Polyclonal Antibody detects endogenous levels of Frizzled-5/8 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human Frizzled-5/8 at AA range: 10-90

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Frizzled5/8

Target: Frizzled5/8 (HYFZD5/8)

Andere Bezeichnung: Frizzled-5/8

Hintergrund: FZD5, C2orf31, Frizzled-5, Fz-5, hFz5, FzE5, FZD8, Frizzled-8, Fz-8, hFz8This intronless gene FZD8 (frizzled class receptor 8) is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. FZD8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.

Molekulargewicht: 75kD

Gen-ID: 8325, 7855

UniProt: Q13467, Q9H461

Pathways: WNT Signalweg