FZD8 Antikörper (AA 460-540)

Produktnummer ABIN7225246

Dieser Anti-FZD8 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von FZD8 in WB, ELISA und IHC (p). Geeignet für Human, Maus und Ratte.

Kurzübersicht für FZD8 Antikörper (AA 460-540) (ABIN7225246)

Target: FZD8 (Frizzled Family Receptor 8 (FZD8))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FZD8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-FZD8 Antikörper

Bindungsspezifität: AA 460-540

Verwendungszweck: Frizzled-8 Polyclonal Antibody

Spezifität: Frizzled-8 Polyclonal Antibody detects endogenous levels of Frizzled-8 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Frizzled-8 at AA range: 460-540

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:5000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu FZD8

Target: FZD8 (Frizzled Family Receptor 8 (FZD8))

Andere Bezeichnung: Frizzled-8

Hintergrund: Rabbit Anti-Frizzled-8 Polyclonal Antibody,FZD8, Frizzled-8, Fz-8, hFz8,This intronless gene FZD8 (frizzled class receptor 8) is a member of the frizzled gene family. Members of this family encode seven-transmembrane domain proteins that are receptors for the Wingless type MMTV integration site family of signaling proteins. Most frizzled receptors are coupled to the beta-catenin canonical signaling pathway. FZD8 is highly expressed in two human cancer cell lines, indicating that it may play a role in several types of cancer. The crystal structure of the extracellular cysteine-rich domain of a similar mouse protein has been determined.,Frizzled-8

Molekulargewicht: observerd band 70kDa

Gen-ID: 8325

UniProt: Q9H461

Pathways: WNT Signalweg