FOXO4 Antikörper (acLys189)

Produktnummer ABIN7228584

Der Kaninchen Polyklonal anti-FOXO4 Antikörper wird verwendet zum Nachweis von FOXO4 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und ELISA.

Kurzübersicht für FOXO4 Antikörper (acLys189) (ABIN7228584)

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXO4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-FOXO4 Antikörper

Bindungsspezifität: acLys189

Verwendungszweck: Rabbit Anti-FoxO4 (Acetyl Lys189) Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of FoxO4 when Acetyl occurs at Lys189

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FoxO4 (Acetyl Lys189) protein at AA range: 189

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:10000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu FOXO4

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Andere Bezeichnung: FoxO4

Hintergrund: Forkhead box protein O4, Fork head domain transcription factor AFX1FOXO4 encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving FOXO4 on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for FOXO4. FOXO4 (Forkhead Box O4) is a Protein Coding gene. Diseases associated with FOXO4 include Balloon Cell Malignant Melanoma and Sarcomatoid Squamous Cell Skin Carcinoma. Among its related pathways are AGE/RAGE pathway and RET signaling.

Molekulargewicht: 55kD

Gen-ID: 4303

UniProt: P98177

Pathways: Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation