FOXO4 Antikörper (acLys189)

Produktnummer ABIN7228584

Der Kaninchen Polyklonal Anti-FOXO4 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, FOXO4 in Proben von Human zu detektieren.

Kurzübersicht für FOXO4 Antikörper (acLys189) (ABIN7228584)

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FOXO4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-FOXO4 Antikörper

Bindungsspezifität: acLys189

Verwendungszweck: FoxO4 (Acetyl Lys189) Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of FoxO4 when Acetyl occurs at Lys189

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human FoxO4 (Acetyl Lys189) protein at AA range: 189

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu FOXO4

Target: FOXO4 (Forkhead Box O4 (FOXO4))

Andere Bezeichnung: FoxO4

Hintergrund: Rabbit Anti-FoxO4 (Acetyl Lys189) Polyclonal Antibody,Forkhead box protein O4, Fork head domain transcription factor AFX1,FOXO4 encodes a member of the O class of winged helix/forkhead transcription factor family. Proteins encoded by this class are regulated by factors involved in growth and differentiation indicating they play a role in these processes. A translocation involving FOXO4 on chromosome X and the homolog of the Drosophila trithorax gene, encoding a DNA binding protein, located on chromosome 11 is associated with leukemia. Multiple transcript variants encoding different isoforms have been found for FOXO4. FOXO4 (Forkhead Box O4) is a Protein Coding gene. Diseases associated with FOXO4 include Balloon Cell Malignant Melanoma and Sarcomatoid Squamous Cell Skin Carcinoma. Among its related pathways are AGE/RAGE pathway and RET signaling.,FoxO4

Molekulargewicht: observerd band 55kDa

Gen-ID: 4303

UniProt: P98177

Pathways: Zellzyklus, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Regulation of Muscle Cell Differentiation