FGF10 Antikörper (AA 120-200)

Produktnummer ABIN7228512

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch FGF10 in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human, Ratte und Maus.

Kurzübersicht für FGF10 Antikörper (AA 120-200) (ABIN7228512)

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Reaktivität: Human, Ratte, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FGF10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-FGF10 Antikörper

Bindungsspezifität: AA 120-200

Verwendungszweck: Rabbit Anti-FGF10 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of FGF10 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FGF10 protein at AA range: 120-200

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu FGF10

Target: FGF10 (Fibroblast Growth Factor 10 (FGF10))

Andere Bezeichnung: FGF10

Hintergrund: Fibroblast growth factor 10, FGF-10, Keratinocyte growth factor 2The protein encoded by FGF10 is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. This protein exhibits mitogenic activity for keratinizing epidermal cells, but essentially no activity for fibroblasts, which is similar to the biological activity of FGF7. Studies of the mouse homolog of suggested that FGF10 is required for embryonic epidermal morphogenesis including brain development, lung morphogenesis, and initiation of lim bud formation. FGF10 is also implicated to be a primary factor in the process of wound healing.

Molekulargewicht: 22kD

Gen-ID: 2255

UniProt: O15520

Pathways: RTK Signalweg, Fc-epsilon Rezeptor Signalübertragung, EGFR Signaling Pathway, Neurotrophin Signalübertragung, Stem Cell Maintenance, Tube Formation, Positive Regulation of Response to DNA Damage Stimulus