FAP Antikörper (AA 300-380)

Produktnummer ABIN7220440

Der Kaninchen Polyklonal anti-FAP Antikörper wird verwendet zum Nachweis von FAP in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IHC, ELISA und IF.

Kurzübersicht für FAP Antikörper (AA 300-380) (ABIN7220440)

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAP Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-FAP Antikörper

Bindungsspezifität: AA 300-380

Verwendungszweck: Rabbit Anti-Seprase Polyclonal Antibody

Spezifität: Seprase Polyclonal Antibody detects endogenous levels of Seprase protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human Seprase at AA range: 300-380

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC: 1:100-300,ELISA 1:20000,IF 1:100-300,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu FAP

Target: FAP (Fibroblast Activation Protein, alpha (FAP))

Andere Bezeichnung: Seprase

Hintergrund: FAP, Seprase, 170 kDa melanoma membrane-bound gelatinase, Fibroblast activation protein alpha, Integral membrane serine proteaseThe fibroblast activation protein alpha encoded by FAP is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. Seprase is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Alternatively spliced transcript variants encoding different isoforms have been found for FAP.

Molekulargewicht: 90kD

Gen-ID: 2191

UniProt: Q12884

Pathways: Tube Formation