FGFR1OP Antikörper (AA 310-390)
Kurzübersicht für FGFR1OP Antikörper (AA 310-390) (ABIN7214926)
Target
Alle FGFR1OP Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 310-390
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Verwendungszweck
- FOP Polyclonal Antibody
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Spezifität
- FOP Polyclonal Antibody detects endogenous levels of FOP protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the C-terminal region of human FOP at AA range: 310-390
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- FGFR1OP (FGFR1 Oncogene Partner (FGFR1OP))
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Andere Bezeichnung
- FOP
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Hintergrund
- Rabbit Anti-FOP Polyclonal Antibody,FGFR1OP, FOP, FGFR1 oncogene partner,FGFR1OP encodes a largely hydrophilic centrosomal protein, FGFR1 oncogene partner, that is required for anchoring microtubules to subcellular structures. A t(6,8)(q27,p11) chromosomal translocation, fusing this gene and the fibroblast growth factor receptor 1 (FGFR1) gene, has been found in cases of myeloproliferative disorder. The resulting chimeric protein contains the N-terminal leucine-rich region of this encoded protein fused to the catalytic domain of FGFR1. Alterations in this gene may also be associated with Crohn's disease, Graves' disease, and vitiligo. Alternatively spliced transcript variants that encode different proteins have been identified.,FGFR1 oncogene partner
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Molekulargewicht
- observerd band 43kDa
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Gen-ID
- 11116
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UniProt
- O95684
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Pathways
- M Phase, Maintenance of Protein Location, SARS-CoV-2 Protein Interaktom
Target
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