FAT1 Antikörper (AA 1140-1220)

Produktnummer ABIN7228488

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch FAT1 in IHC (p). Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für FAT1 Antikörper (AA 1140-1220) (ABIN7228488)

Target: FAT1 (FAT Tumor Suppressor Homolog 1 (FAT1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FAT1 Antikörper ist unkonjugiert

Applikation: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-FAT1 Antikörper

Bindungsspezifität: AA 1140-1220

Verwendungszweck: FAT1 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of FAT1 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human FAT1 protein at AA range: 1140-1220

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:50-1:300).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu FAT1

Target: FAT1 (FAT Tumor Suppressor Homolog 1 (FAT1))

Andere Bezeichnung: FAT1

Hintergrund: Rabbit Anti-FAT1 Polyclonal Antibody,Protocadherin Fat 1, Cadherin family member 7, Cadherin-related tumor suppressor homolog, Protein fat homolog, Protocadherin Fat 1, nuclear form,FAT1 is an ortholog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. FAT1 product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, FAT1 product has five epidermal growth factor (EGF)-like repeats and one laminin A-G domain. FAT1 is expressed at high levels in a number of fetal epithelia. Its product probably functions as an adhesion molecule and/or signaling receptor, and is likely to be important in developmental processes and cell communication. Transcript variants derived from alternative splicing and/or alternative promoter usage exist, but they have not been fully described.,FAT1

Molekulargewicht: observerd band 504kDa

Gen-ID: 2195

UniProt: Q14517