FAT Atypical Cadherin 2 (FAT2) Antikörper

Produktnummer ABIN7228490

Der Kaninchen Polyklonal anti-FAT Atypical Cadherin 2 Antikörper wird verwendet zum Nachweis von FAT Atypical Cadherin 2 in Proben von Human, Maus und Ratte. Er wurde validiert für IF und IHC.

Kurzübersicht für FAT Atypical Cadherin 2 (FAT2) Antikörper (ABIN7228490)

Target: FAT Atypical Cadherin 2 (FAT2)

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Unkonjugiert

Applikation: Immunofluorescence (IF), Immunohistochemistry (IHC)

Produktdetails

Verwendungszweck: Rabbit Anti-FAT2 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of FAT2 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human FAT2 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC 1:50-300,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Antigendetails

Target: FAT Atypical Cadherin 2 (FAT2)

Andere Bezeichnung: FAT2

Hintergrund: Protocadherin Fat 2, hFat2, Cadherin family member 8, Multiple epidermal growth factor-like domains protein 1, Multiple EGF-like domains protein 1FAT2 gene is the second identified human homolog of the Drosophila fat gene, which encodes a tumor suppressor essential for controlling cell proliferation during Drosophila development. The gene product is a member of the cadherin superfamily, a group of integral membrane proteins characterized by the presence of cadherin-type repeats. In addition to containing 34 tandem cadherin-type repeats, the gene product has two epidermal growth factor (EGF)-like repeats and one laminin G domain. This protein most likely functions as a cell adhesion molecule, controlling cell proliferation and playing an important role in cerebellum development.

Molekulargewicht: 478kD

Gen-ID: 2196

UniProt: Q9NYQ8