ERAP1 Antikörper (AA 410-490)

Produktnummer ABIN7214794

Der Kaninchen Polyklonal anti-ERAP1 Antikörper (ABIN7214794) detektiert spezifisch ERAP1 in WB, ELISA, IHC und IF. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus und Ratte.

Kurzübersicht für ERAP1 Antikörper (AA 410-490) (ABIN7214794)

Target: ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser ERAP1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-ERAP1 Antikörper

Bindungsspezifität: AA 410-490

Verwendungszweck: Rabbit Anti-ERAP1 Polyclonal Antibody

Spezifität: ERAP1 Polyclonal Antibody detects endogenous levels of ERAP1 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the Internal region of human ERAP1 at AA range: 410-490

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,IF 1:200-1:1000,ELISA 1:20000,Not yet tested in other applications.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu ERAP1

Target: ERAP1 (Endoplasmic Reticulum Aminopeptidase 1 (ERAP1))

Andere Bezeichnung: ERAP1

Hintergrund: ERAP1, APPILS, ARTS1, KIAA0525, Endoplasmic reticulum aminopeptidase 1, ARTS-1, Adipocyte-derived leucine aminopeptidase, A-LAP, Aminopeptidase PILS, Puromycin-insensitive leucyl-specific aminopeptidase, PILS-AP, Type 1 tumor necrosis factoEndoplasmic reticulum aminopeptidase 1 encoded by ERAP1 is an aminopeptidase involved in trimming HLA class I-binding precursors so that they can be presented on MHC class I molecules. The encoded protein acts as a monomer or as a heterodimer with ERAP2. This protein may also be involved in blood pressure regulation by inactivation of angiotensin II. Three transcript variants encoding two different isoforms have been found for ERAP1.

Molekulargewicht: 107kD

Gen-ID: 51752

UniProt: Q9NZ08