Endoglin Antikörper (AA 370-430)

Produktnummer ABIN7228398

Dieser Anti-Endoglin Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Endoglin in WB, ELISA und IHC (p). Geeignet für Human.

Kurzübersicht für Endoglin Antikörper (AA 370-430) (ABIN7228398)

Target: Endoglin (ENG)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Endoglin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Endoglin Antikörper

Bindungsspezifität: AA 370-430

Verwendungszweck: Endoglin Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of Endoglin

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human Endoglin protein at AA range: 370-430

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:500-1:200), ELISA (1:10000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol as stabilizer.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Endoglin

Target: Endoglin (ENG)

Andere Bezeichnung: Endoglin

Hintergrund: Rabbit Anti-Endoglin Polyclonal Antibody,Endoglin, CD antigen CD105,Endoglin encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in Endoglin cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. Endoglin may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for Endoglin.,Endoglin

Molekulargewicht: observerd band 70kDa

Gen-ID: 2022

UniProt: P17813