EDAR Antikörper (AA 50-130)

Produktnummer ABIN7228346

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch EDAR in WB und ELISA. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für EDAR Antikörper (AA 50-130) (ABIN7228346)

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EDAR Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-EDAR Antikörper

Bindungsspezifität: AA 50-130

Verwendungszweck: Rabbit Anti-EDAR Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of EDAR protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human EDAR protein at AA range: 50-130

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu EDAR

Target: EDAR (Ectodysplasin A Receptor (EDAR))

Andere Bezeichnung: EDAR

Hintergrund: Tumor necrosis factor receptor superfamily member EDAR, Anhidrotic ectodysplasin receptor 1, Downless homolog, EDA-A1 receptor, Ectodermal dysplasia receptor, Ectodysplasin-A receptorEDAR encodes a member of the tumor necrosis factor receptor family. The encoded transmembrane protein is a receptor for the soluble ligand ectodysplasin A, and can activate the nuclear factor-kappaB, JNK, and caspase-independent cell death pathways. It is required for the development of hair, teeth, and other ectodermal derivatives. Mutations in EDAR result in autosomal dominant and recessive forms of hypohidrotic ectodermal dysplasia.

Molekulargewicht: 49kD

Gen-ID: 10913

UniProt: Q9UNE0

Pathways: Tube Formation, Ubiquitin Proteasome Pathway