Dysferlin Antikörper (AA 1950-2030)

Produktnummer ABIN7225232

Dieser Anti-Dysferlin Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von Dysferlin in WB, ELISA und IF. Geeignet für Human und Maus.

Kurzübersicht für Dysferlin Antikörper (AA 1950-2030) (ABIN7225232)

Target: Dysferlin (DYSF)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Dysferlin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (IF)

Produktdetails anti-Dysferlin Antikörper

Bindungsspezifität: AA 1950-2030

Verwendungszweck: Dysferlin Polyclonal Antibody

Spezifität: Dysferlin Polyclonal Antibody detects endogenous levels of Dysferlin protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the C-terminal region of human Dysferlin at AA range: 1950-2030

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IF (1:200-1:1000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Dysferlin

Target: Dysferlin (DYSF)

Andere Bezeichnung: Dysferlin

Hintergrund: Rabbit Anti-Dysferlin Polyclonal Antibody,DYSF, FER1L1, Dysferlin, Dystrophy-associated fer-1-like protein, Fer-1-like protein 1,The protein encoded by DYSF (dysferlin) belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by DYSF binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in DYSF have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants.,Dysferlin

Molekulargewicht: observerd band 240kDa

Gen-ID: 8291

UniProt: O75923