Dysferlin Antikörper

Produktnummer ABIN7266868

Produktdetails anti-Dysferlin Antikörper

Target: Dysferlin (DYSF)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Monoklonal

Konjugat: Dieser Dysferlin Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC)

Verwendungszweck: Dysferlin (Romeo) Rabbit mAb

Kreuzreaktivität: Human, Maus

Produktmerkmale: Monoclonal Antibodies

Aufreinigung: Affinity purification

Immunogen: A synthesized peptide derived from human Dysferlin (Romeo)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB,1:500 - 1:2000,IHC,1:50 - 1:200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: PBS with 0.02 % sodium azide,0.05 % BSA,50 % glycerol, pH 7.3.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Avoid freeze / thaw cycles.

Details zu Dysferlin

Target: Dysferlin (DYSF)

Andere Bezeichnung: DYSF (DYSF Produkte)

Synonyme: DYSF antikoerper, fb73b05 antikoerper, wu:fb73b05 antikoerper, si:rp71-50c18.1 antikoerper, DKFZp459E1226 antikoerper, 2310004N10Rik antikoerper, AI604795 antikoerper, D6Pas3 antikoerper, mFLJ00175 antikoerper, FER1L1 antikoerper, LGMD2B antikoerper, MMD1 antikoerper, dysferlin antikoerper, dysferlin, limb girdle muscular dystrophy 2B (autosomal recessive) antikoerper, myoferlin antikoerper, DYSF antikoerper, dysf antikoerper, LOC589501 antikoerper, Dysf antikoerper

Hintergrund: The protein encoded by this gene belongs to the ferlin family and is a skeletal muscle protein found associated with the sarcolemma. It is involved in muscle contraction and contains C2 domains that play a role in calcium-mediated membrane fusion events, suggesting that it may be involved in membrane regeneration and repair. In addition, the protein encoded by this gene binds caveolin-3, a skeletal muscle membrane protein which is important in the formation of caveolae. Specific mutations in this gene have been shown to cause autosomal recessive limb girdle muscular dystrophy type 2B (LGMD2B) as well as Miyoshi myopathy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2008],FER1L1, LGMD2B, MMD1,Cell Biology & Developmental Biology,DYSF

Molekulargewicht: 280kDa

Gen-ID: 8291

UniProt: O75923