DPYSL2 Antikörper (pThr509)

Produktnummer ABIN7220080

Der Kaninchen Polyklonal anti-DPYSL2 Antikörper wird verwendet zum Nachweis von DPYSL2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, ELISA, IHC und IF.

Kurzübersicht für DPYSL2 Antikörper (pThr509) (ABIN7220080)

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPYSL2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (IHC), Immunofluorescence (IF)

Produktdetails anti-DPYSL2 Antikörper

Bindungsspezifität: pThr509

Verwendungszweck: Rabbit Anti-CRMP-2 (phospho Thr509) Polyclonal Antibody

Spezifität: Phospho-CRMP-2 (T509) Polyclonal Antibody detects endogenous levels of CRMP-2 protein only when phosphorylated at T509.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from human CRMP-2 Phospho-Thr509

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu DPYSL2

Target: DPYSL2 (Dihydropyrimidinase-Like 2 (DPYSL2))

Andere Bezeichnung: CRMP-2

Hintergrund: DPYSL2, CRMP2, ULIP2, Dihydropyrimidinase-related protein 2, DRP-2, Collapsin response mediator protein 2, CRMP-2, N2A3, Unc-33-like phosphoprotein 2, ULIP-2DPYSL2 encodes a member of the collapsin response mediator protein family. Collapsin response mediator proteins form homo- and hetero-tetramers and facilitate neuron guidance, growth and polarity. The encoded protein promotes microtubule assembly and is required for Sema3A-mediated growth cone collapse, and also plays a role in synaptic signaling through interactions with calcium channels. DPYSL2 has been implicated in multiple neurological disorders, and hyperphosphorylation of the encoded protein may play a key role in the development of Alzheimer's disease. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.

Molekulargewicht: 50kD

Gen-ID: 1808

UniProt: Q16555

Pathways: Regulation of Cell Size