DKK2 Antikörper
Kurzübersicht für DKK2 Antikörper (ABIN7228226)
Target
Alle DKK2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Verwendungszweck
- DKK2 Polyclonal Antibody
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Spezifität
- The antibody detects endogenous levels of DKK2 protein
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Aufreinigung
- The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen
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Immunogen
- Synthesized peptide derived from part region of human DKK2 protein
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- DKK2 (Dickkopf 2 Homolog (DKK2))
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Andere Bezeichnung
- DKK2
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Hintergrund
- Rabbit Anti-DKK2 Polyclonal Antibody,Dickkopf-related protein 2, Dickkopf-2, Dkk-2, hDkk-2,DKK2 encodes Dickkopf WNT Signaling Pathway Inhibitor 2 that is a member of the dickkopf family. The secreted protein contains two cysteine rich regions and is involved in embryonic development through its interactions with the Wnt signaling pathway. It can act as either an agonist or antagonist of Wnt/beta-catenin signaling, depending on the cellular context and the presence of the co-factor kremen 2. Activity of this protein is also modulated by binding to the Wnt co-receptor LDL-receptor related protein 6 (LRP6).,DKK2
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Molekulargewicht
- observerd band 28kDa
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Gen-ID
- 27123
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UniProt
- Q9UBU2
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Pathways
- WNT Signalweg
Target
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