Diazepam Binding Inhibitor Antikörper (Internal Region)

Produktnummer ABIN7213444

Der Kaninchen Polyklonal Anti-Diazepam Binding Inhibitor Antikörper wurde für WB, ELISA und IHC (p) validiert. Er ist geeignet, Diazepam Binding Inhibitor in Proben von Human zu detektieren.

Kurzübersicht für Diazepam Binding Inhibitor Antikörper (Internal Region) (ABIN7213444)

Target: Diazepam Binding Inhibitor (DBI)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Diazepam Binding Inhibitor Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-Diazepam Binding Inhibitor Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: ACBP Polyclonal Antibody

Spezifität: ACBP Polyclonal Antibody detects endogenous levels of ACBP protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human ACBP

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Diazepam Binding Inhibitor

Target: Diazepam Binding Inhibitor (DBI)

Andere Bezeichnung: ACBP

Hintergrund: Rabbit Anti-ACBP Polyclonal Antibody,DBI, Acyl-CoA-binding protein, ACBP, Diazepam-binding inhibitor, DBI, Endozepine, EP,DBI encodes diazepam binding inhibitor (diazepam binding inhibitor, acyl-CoA binding protein), a protein that is regulated by hormones and is involved in lipid metabolism and the displacement of beta-carbolines and benzodiazepines, which modulate signal transduction at type A gamma-aminobutyric acid receptors located in brain synapses. The protein is conserved from yeast to mammals, with the most highly conserved domain consisting of seven contiguous residues that constitute the hydrophobic binding site for medium- and long-chain acyl-Coenzyme A esters. Diazepam binding inhibitor is also known to mediate the feedback regulation of pancreatic secretion and the postprandial release of cholecystokinin, in addition to its role as a mediator in corticotropin-dependent adrenal steroidogenesis. Three pseudogenes located on chromosomes 6, 8 and 16 have been identified. Multiple transcript variants encoding different isoforms have been described for DBI.,Acyl-CoA-binding protein

Gen-ID: 1622

UniProt: P07108