DPPA4 Antikörper

Produktnummer ABIN7228284

Dieser Anti-DPPA4 Antikörper ist ein Kaninchen Polyklonal Antikörper zur Detektion von DPPA4 in WB und ELISA. Geeignet für Human, Maus und Ratte.

Kurzübersicht für DPPA4 Antikörper (ABIN7228284)

Target: DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DPPA4 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-DPPA4 Antikörper

Verwendungszweck: DPPA4 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of DPPA4 protein

Aufreinigung: The antibody was affinity-purified from rabbit serum by affinity-chromatography using specific immunogen

Immunogen: Synthesized peptide derived from part region of human DPPA4 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:5000-1:20000).

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, pH 7.4, containing 0.02 % Sodium Azide as preservative and 50 % Glycerol.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu DPPA4

Target: DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))

Andere Bezeichnung: DPPA4

Hintergrund: Rabbit Anti-DPPA4 Polyclonal Antibody,Developmental pluripotency-associated protein 4,DPPA4 encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18. but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of DPPA4 have been identified. Alternative splicing results in multiple transcript variants.,DPPA4

Molekulargewicht: observerd band 33kDa

Gen-ID: 55211

UniProt: Q7L190