DPPA4 Antikörper (AA 15-304)
Kurzübersicht für DPPA4 Antikörper (AA 15-304) (ABIN6139802)
Target
Alle DPPA4 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 15-304
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Sequenz
- KGKEWTSTEK SREEDQQASN QPNSIALPGT SAKRTKEKMS IKGSKVLCPK KKAEHTDNPR PQKKIPIPPL PSKLPPVNLI HRDILRAWCQ QLKLSSKGQK LDAYKRLCAF AYPNQKDFPS TAKEAKIRKS LQKKLKVEKG ETSLQSSETH PPEVALPPVG EPPALENSTA LLEGVNTVVV TTSAPEALLA SWARISARAR TPEAVESPQE ASGVRWCVVH GKSLPADTDG WVHLQFHAGQ AWVPEKQEGR VSALFLLPAS NFPPPHLEDN MLCPKCVHRN KVLIKSLQWE
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Kreuzreaktivität
- Human, Maus, Ratte
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Produktmerkmale
- Polyclonal Antibodies
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Aufreinigung
- Affinity purification
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Immunogen
- Recombinant fusion protein containing a sequence corresponding to amino acids 15-304 of human DPPA4 (NP_060659.3).
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Isotyp
- IgG
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Applikationshinweise
- WB,1:500 - 1:2000
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- PBS with 0.02 % sodium azide,50 % glycerol, pH 7.3.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Avoid freeze / thaw cycles.
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- DPPA4 (Developmental Pluripotency Associated 4 (DPPA4))
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Andere Bezeichnung
- DPPA4
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Hintergrund
- This gene encodes a nuclear factor that is involved in the maintenance of pluripotency in stem cells and essential for embryogenesis. The encoded protein has a scaffold-attachment factor A/B, acinus and PIAS (SAP) domain that binds DNA and is thought to modify chromatin. Mice with a homozygous knockout of the orthologous gene die during late embryonic development or within hours after birth. Knockout embryos are normal in size at embryonic day 18.5 but exhibit skeletal and lung tissue abnormalities. This gene, when mutated, is highly expressed in embryonal carcinomas, pluripotent germ cell tumors, and other cancers and is thought to play an important role in tumor progression. Multiple pseudogenes of this gene have been identified. Alternative splicing results in multiple transcript variants.,DPPA4,2410091M23Rik,Cell Biology & Developmental Biology,Stem Cells,Embryonic Stem Cells,DPPA4
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Molekulargewicht
- 33 kDa
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Gen-ID
- 55211
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UniProt
- Q7L190
Target
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