Desmoglein 2 Antikörper (AA 370-450)

Produktnummer ABIN7220094

Dieser Kaninchen Polyklonal Antikörper erkennt spezifisch Desmoglein 2 in WB und ELISA. Er zeigt eine Reaktivität gegenüber Human.

Kurzübersicht für Desmoglein 2 Antikörper (AA 370-450) (ABIN7220094)

Target: Desmoglein 2 (DSG2)

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Desmoglein 2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-Desmoglein 2 Antikörper

Bindungsspezifität: AA 370-450

Verwendungszweck: Dsg2 Polyclonal Antibody

Spezifität: Dsg2 Polyclonal Antibody detects endogenous levels of Dsg2 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Dsg2 at AA range: 370-450

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:40000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu Desmoglein 2

Target: Desmoglein 2 (DSG2)

Andere Bezeichnung: Dsg2

Hintergrund: Rabbit Anti-Dsg2 Polyclonal Antibody,DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGC,DSG2 encodes a member of the desmoglein family and cadherin cell adhesion molecule superfamily of proteins. Desmogleins are calcium-binding transmembrane glycoprotein components of desmosomes, cell-cell junctions between epithelial, myocardial, and other cell types. The encoded preproprotein is proteolytically processed to generate the mature glycoprotein. DSG2 is present in a gene cluster with other desmoglein gene family members on chromosome 18. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10.,Desmoglein-2

Molekulargewicht: observerd band 140kDa

Gen-ID: 1829

UniProt: Q14126

Pathways: Cell-Cell Junction Organization