DEFa3 Antikörper (Internal Region)

Produktnummer ABIN7220016

Der Kaninchen Polyklonal Anti-DEFa3 Antikörper wurde für ELISA und IHC (p) validiert. Er ist geeignet, DEFa3 in Proben von Human zu detektieren.

Kurzübersicht für DEFa3 Antikörper (Internal Region) (ABIN7220016)

Target: DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DEFa3 Antikörper ist unkonjugiert

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Produktdetails anti-DEFa3 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: Defensin α3 Polyclonal Antibody

Spezifität: Defensin α3 Polyclonal Antibody detects endogenous levels of Defensin α3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human Defensin alpha3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu DEFa3

Target: DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))

Andere Bezeichnung: Defensin alpha3

Hintergrund: Rabbit Anti-Defensin α3 Polyclonal Antibody,DEFA3, DEF3, Neutrophil defensin 3, Defensin, alpha 3, HNP-3, HP-3, HP3,Defensins are a family of antimicrobial and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Neutrophil defensin 3 encoded by DEFA3, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. DEFA3 differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation.,Neutrophil defensin 3

Gen-ID: 1668

UniProt: P59666

Pathways: Cellular Response to Molecule of Bacterial Origin