DEFa3 Antikörper (C-Term)

Produktnummer ABIN1537232

Der Kaninchen Polyklonal anti-DEFa3 Antikörper wird verwendet zum Nachweis von DEFa3 in Proben von Human. Er wurde validiert für WB und IHC (p).

Kurzübersicht für DEFa3 Antikörper (C-Term) (ABIN1537232)

Target: DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DEFa3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Klon: RB30594

Produktdetails anti-DEFa3 Antikörper

Bindungsspezifität: AA 38-65, C-Term

Aufreinigung: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This DEFA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-65 amino acids from the C-terminal region of human DEFA3.

Isotyp: Ig Fraction

Anwendungsinformationen

Applikationshinweise: WB: 1:1000. IHC-P-Leica: 1:500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: DEFA3 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, keep at -20 °C.

Haltbarkeit: 6 months

Details zu DEFa3

Target: DEFa3 (Defensin, alpha 3, Neutrophil-Specific (DEFa3))

Andere Bezeichnung: DEFA3

Hintergrund: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation.

Molekulargewicht: 10245

Gen-ID: 1668

NCBI Accession: NP_005208

UniProt: P59666

Pathways: Cellular Response to Molecule of Bacterial Origin