COX10 Antikörper (Internal Region)

Produktnummer ABIN7219600

Der Kaninchen Polyklonal Anti-COX10 Antikörper wurde für WB und ELISA validiert. Er ist geeignet, COX10 in Proben von Human zu detektieren.

Kurzübersicht für COX10 Antikörper (Internal Region) (ABIN7219600)

Target: COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser COX10 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA

Produktdetails anti-COX10 Antikörper

Bindungsspezifität: Internal Region

Verwendungszweck: COX10 Polyclonal Antibody

Spezifität: COX10 Polyclonal Antibody detects endogenous levels of COX10 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen

Immunogen: Synthesized peptide derived from the Internal region of human COX10

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), ELISA (1:10000). Not yet tested in other applications.

Kommentare:

Primary Antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Details zu COX10

Target: COX10 (Cytochrome C Oxidase Assembly Homolog 10 (COX10))

Andere Bezeichnung: COX10

Hintergrund: Rabbit Anti-COX10 Polyclonal Antibody,COX10, Protoheme IX farnesyltransferase, mitochondrial, Heme O synthase,Cytochrome c oxidase (COX), the terminal component of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. This component is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in electron transfer, and the nuclear-encoded subunits may function in the regulation and assembly of the complex. COX10 encodes heme A: farnesyltransferase, which is not a structural subunit but required for the expression of functional COX and functions in the maturation of the heme A prosthetic group of COX. COX10, heme A: farnesyltransferase cytochrome c oxidase assembly factor is predicted to contain 7-9 transmembrane domains localized in the mitochondrial inner membrane. A gene mutation, which results in the substitution of a lysine for an asparagine (N204K), is identified to be responsible for cytochrome c oxidase deficiency. In addition, this gene is disrupted in patients with CMT1A (Charcot-Marie-Tooth type 1A) duplication and with HNPP (hereditary neuropathy with liability to pressure palsies) deletion.,Protoheme IX farnesyltransferase mitochondrial

Molekulargewicht: observerd band 49kDa

Gen-ID: 1352

UniProt: Q12887