Der Kaninchen Polyklonal anti-Cyclin-Dependent Kinase 11A Antikörper wird verwendet zum Nachweis von Cyclin-Dependent Kinase 11A in Proben von Human und Maus. Er wurde validiert für ELISA, WB, IHC und IF.
CDK11A
Reaktivität: Human
Wirt: Kaninchen
Polyclonal
FITC
Applikationshinweise
Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-1:2000,IHC 1:100-1:300,ELISA 1:20000,IF 1:50-200
Beschränkungen
Nur für Forschungszwecke einsetzbar
Format
Liquid
Konzentration
1 mg/mL
Buffer
Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.
Konservierungsmittel
Sodium azide
Vorsichtsmaßnahmen
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Lagerung
-20 °C
Informationen zur Lagerung
Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
Haltbarkeit
12 months
Target
Cyclin-Dependent Kinase 11A (CDK11A)
Andere Bezeichnung
PITSLRE
Hintergrund
CDK11B, CDC2L1, CDK11, PITSLREA, PK58, Cyclin-dependent kinase 11B, Cell division cycle 2-like protein kinase 1, CLK-1, Cell division protein kinase 11B, Galactosyltransferase-associated protein kinase p58/GTA, PITSLRE serine/threonine-protCDK11B encodes a member of the serine/threonine protein kinase family. Members of this kinase family are known to be essential for eukaryotic cell cycle control. Due to a segmental duplication, CDK11B shares very high sequence identity with a neighboring gene. These two genes are frequently deleted or altered in neuroblastoma. Cyclin dependent kinase 11B encoded by CDK11B can be cleaved by caspases and may play a role in cell apoptosis. Alternative splicing results in multiple transcript variants.