Cyclin B3 Antikörper

Produktnummer ABIN7227656

Der Kaninchen Polyklonal anti-Cyclin B3 Antikörper wird verwendet zum Nachweis von Cyclin B3 in Proben von Maus und Human. Er wurde validiert für ELISA und WB.

Kurzübersicht für Cyclin B3 Antikörper (ABIN7227656)

Target: Cyclin B3 (CCNB3)

Reaktivität: Maus, Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cyclin B3 Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB)

Produktdetails anti-Cyclin B3 Antikörper

Verwendungszweck: Rabbit Anti-CCNB3 Polyclonal Antibody

Spezifität: The antibody detects endogenous levels of CCNB3 protein

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from part region of human CCNB3 protein

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,ELISA 1:5000-20000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: PBS, 50 % glycerol, 0.05 % Proclin 300, 0.05 %BSA

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Cyclin B3

Target: Cyclin B3 (CCNB3)

Andere Bezeichnung: CCNB3

Hintergrund: G2/mitotic-specific cyclin-B3The protein encoded by this gene belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as positive regulators of cyclin-dependent kinases (CDKs), and thereby play an essential role in the control of the cell cycle. Different cyclins exhibit distinct expression and degradation patterns, which contribute to the temporal coordination of each mitotic event. Studies of similar genes in chicken and drosophila suggest that this cyclin may associate with CDC2 and CDK2 kinases, and may be required for proper spindle reorganization and restoration of the interphase nucleus. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Molekulargewicht: 153kD

Gen-ID: 85417

UniProt: Q8WWL7

Pathways: Zellzyklus, Chromatin Binding