Cullin 4B Antikörper (Internal Region)
Kurzübersicht für Cullin 4B Antikörper (Internal Region) (ABIN7217916)
Target
Alle Cullin 4B (CUL4B) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Internal Region
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Verwendungszweck
- CUL-4B Polyclonal Antibody
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Spezifität
- CUL-4B Polyclonal Antibody detects endogenous levels of CUL-4B protein.
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Aufreinigung
- The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen
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Immunogen
- Synthesized peptide derived from the Internal region of human CUL-4B
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Isotyp
- IgG
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB (1:500-1:2000), IHC-P (1:100-1:300), ELISA (1:20000). Not yet tested in other applications.
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Kommentare
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Primary Antibody
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 mg/mL
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Buffer
- PBS containing 50 % Glycerol, 0.5 % BSA and 0.02 % Sodium Azide.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.
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- Cullin 4B (CUL4B)
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Andere Bezeichnung
- CUL-4B
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Hintergrund
- Rabbit Anti-CUL-4B Polyclonal Antibody,CUL4B, KIAA0695, Cullin-4B, CUL-4B,CUL4B is a member of the cullin family. The cullin 4B forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.,Cullin-4B
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Molekulargewicht
- observerd band 110kDa
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Gen-ID
- 8450
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UniProt
- Q13620
Target
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