Cullin 3 Antikörper (AA 1-80)

Produktnummer ABIN7214382

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Cullin 3 in WB, IHC, ELISA und IF. Es zeigt Reaktivität gegenüber Proben von Human und Maus.

Kurzübersicht für Cullin 3 Antikörper (AA 1-80) (ABIN7214382)

Target: Cullin 3 (CUL3)

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Cullin 3 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), ELISA, Immunofluorescence (IF)

Produktdetails anti-Cullin 3 Antikörper

Bindungsspezifität: AA 1-80

Verwendungszweck: Rabbit Anti-CUL-3 Polyclonal Antibody

Spezifität: CUL-3 Polyclonal Antibody detects endogenous levels of CUL-3 protein.

Aufreinigung: The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Immunogen: Synthesized peptide derived from the N-terminal region of human CUL-3 at AA range: 1-80

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator. Suggested starting dilutions are as follows: WB 1:500-2000,IHC 1:100-1:300,ELISA 1:5000,IF 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 mg/mL

Buffer: Liquid in PBS containing 50 % glycerol, 0.5 % BSA and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Stable for one year at -20°C from date of shipment. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Aliquot to avoid repeated freezing and thawing.

Haltbarkeit: 12 months

Details zu Cullin 3

Target: Cullin 3 (CUL3)

Andere Bezeichnung: CUL-3

Hintergrund: CUL3, KIAA0617, Cullin-3, CUL-3CUL3 encodes a member of the cullin protein family. Cullin 3 plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for CUL3.

Molekulargewicht: 90kD

Gen-ID: 8452

UniProt: Q13618

Pathways: M Phase